The way I read the Constitution, we can't amend it to abolish the Senate. But we should be able to curtail its role. I propose a constitutional amendment to limit the Senate to voting up or down on bills generated by the House of Representatives. There wouldn't be any Senate versions or amendments or reconciliation process, just yea or nay on the bills.
Also, as Robin Williams has suggested, Senators should wear jackets with the logos of the special interests who own them just like NASCAR drivers.